PURINERGIC SIGNALING IN MAST CELL DEGRANULATION AND ASTHMA

Purinergic Signaling in Mast Cell Degranulation and Asthma

Mast cells are responsible for the majority of allergic conditions.It was originally thought that almost all allergic events were mediated directly only via the high-affinity immunoglobulin E receptors.However, recent evidence showed that many other receptors, such as G protein-coupled receptors and ligand-gated ion channels, are also directly invo

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Social axioms and coping strategies: the case of a Greek sample

Social axioms are individual assessments of psychological, social, material and spiritual reality expressed as generalized beliefs or assertions about the relationship between two entities or concepts.This study explores how social axioms are associated with coping styles in a Greek sample composed of students and adults.Previous studies of how soc

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Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control

The death of cardiomyocytes either through apoptosis or necroptosis is the pathological feature of cardiac ischemia-reperfusion (I/R) injury.Phosphoglycerate mutase 5 (PGAM5), a mitochondrially-localized serine/threonine-protein phosphatase, functions as a novel inducer of necroptosis.However, intense debate exists regarding the effect of PGAM5 on

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HIV due to female sex work: regional and global estimates.

IntroductionFemale sex TV Connect workers (FSWs) are at high risk of HIV infection.Our objective was to determine the proportion of HIV prevalence in the general female adult population that is attributable to the occupational exposure of female sex work, due to unprotected sexual intercourse.MethodsPopulation attributable fractions of HIV prevalen

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